Tohoku University Technology: Lactic Acid Bacteria that Improve Mitochondrial Function: T23-024
Aim to prevent various diseases through daily meals.
Mitochondria, responsible for energy production, increase the production of reactive oxygen species (ROS) when their function declines. ROS are associated with the onset and worsening of diseases such as neurodegenerative disorders, diabetes, and cancer. Notably, the decline in mitochondrial activity in intestinal epithelial cells has been shown to be related not only to intestinal diseases but also to systemic diseases. Until now, there have been no examples of simultaneously analyzing multiple food components that affect mitochondrial function in intestinal epithelial cells. The inventors established a method to detect components that have the effect of suppressing ROS production using porcine intestinal epithelial cells and conducted screenings. As a result, they revealed that FFIG35 (Ligilactobacillus salivarius), a type of lactic acid bacteria in their laboratory, suppresses ROS production and improves cellular oxygen consumption and ATP production. By incorporating this lactic acid bacteria into food, it is expected to prevent various diseases and contribute to extending healthy lifespan. Additionally, due to its mechanism of acting on the epithelium to improve mitochondrial function, there is potential for it to be utilized as an external agent (such as in cosmetics or bath additives).
- Company：Tohoku Techno Arch Co., Ltd.
- Price：Other
